Shure is not an english word so don't ever use it. Sure is like how you understand or use it to confirm something. example: are you sure about your choice of dress?
Affect
1. Affect can be used as a verb. Use it when trying to describe influencing someone or something rather than causing it.
Example: How does the crime rate affect hiring levels by local police forces?
Example: The weather conditions will affect the number of people who come to the county fair this year.
2. Affect can also be used as a noun in one situation - to describe facial expression.
Example: The young man with schizophrenia had a flat affect.
Example: The woman took the news of her husband's sudden death with little affect.
Effect
1. Effect can be used as a noun when you are talking about a result.
Example: What effect did the loss have on the team?
2. Effect can be used if it follows one of these words: "into", "on", "take", "the", "any", "an" as well as "or."
Example: The prescribed medication had an effect on the patient's symptoms.
Example: In analyzing a situation, it is important to take the concepts of cause and effect into consideration.
3. Effect can be used as a verb in one situation - if you want to describe something that was caused.
Example: The new manager effected some positive changes in the office. (This means that the new manager caused some positive changes to take place in the office.)
Read more at http://grammar.yourdictionary.com/style-and-usage/affect-effect-grammar.html#gPSeJYGmS1F9i2ri.99